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The principal components of GBA intercommunication entail the central nervous system (CNS), the peripheral nervous system (PNS), including the autonomic nervous system (ANS) and the enteric nervous system (ENS), the vagus nerve, the neuroendocrine hypothalamic pituitary adrenal (HPA) axis, together play integral roles in this bidirectional signalling network
Common side effects may include nausea, vomiting, diarrhea, constipation, reflux, decreased appetite, or abdominal discomfort
Gradually increasing the dose may help mitigate these effects, allowing the gut to adapt over time (159)
What is Liraglutide (Victoza, Saxenda) and its mechanism of action
Research shows that GLP-1 agonists stimulate fluid secretion in the colon and increase intestinal permeability in some patients
Hangzhou Jiuyuan Gene Engineering (a subsidiary of Huadong Medicine) filed for marketing approval with the National Medical Products Administration (NMPA) in April 2024
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