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No freezing reconstituted peptides causes ice crystal formation that physically shears peptide chains, resulting in irreversible denaturation

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The vitamin is used to treat a variety of conditions related to vitamin B12 deficiency, such as pernicious anemia, which is caused by a lack of intrinsic factor, a protein that is necessary for the absorption of vitamin B12

Zhang XY, Wang DG, Duan YH, Zheng XY, Lin Y, Liang SL (2020) Production of lycopene by metabolically engineered Pichia pastoris

Am J Med Genet C Semin Med Genet 2011 157

Despite these findings, it remains unclear whether OS is a primary factor in the development of PCOS or a secondary consequence of hyperglycemia, insulin resistance, and associated cardiovascular and necrotic complications in these women (124, 132)