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In addition, we successfully degraded the target protein (BRD4) in the tumour by synthesizing JQ1(+)-based PROTAC in situ, resulting in reduced toxicity in the small intestine 22

This does not change the reconstitution process, but it does mean the side effect profiles during dose escalation can differ

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Mice were divided into various groups by computer-generated randomization and then housed and labeled in individual cages

31 The lower H 2 O 2 levels in SHR in this study seems to suggest that H 2 O 2 might not have a significant direct role in the pathogenesis of hypertension in this strain of rat as despite the lower H 2 O 2 levels, systolic blood pressure still increased in the SHR

For example, concurrent use of chloramphenicol (an antibiotic) may attenuate the hematologic response to vitamin B therapy