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Combination therapy produces greater weight loss All treatment groups had improvements in fasting glucose, mean glucose, insulin sensitivity and insulin secretion at 24 weeks

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Preclinical studies have shown that GIP may reduce body weight by reducing food intake and increasing energy consumption, and in combination with GLP-1 receptor agonists, may have a greater effect on patients' blood glucose and body weight

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GLP-1 medications are not universally prohibited, but temporary deferrals apply because these agents affect glucose metabolism, cardiovascular function, and fluid statusfactors that influence plasma stability and recipient safety

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2003 Jun-Aug;24(3-4):233-40

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Taking a dose one day early is unlikely to cause serious problems because the medicine stays in your system for several days

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