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It is synthesised in the cytosol by glutamate-cysteine ligase (EC 6.3.2.2) and glutathione synthetase, with the first, rate-limiting step feedback-inhibited by glutathione itself and intracellular concentrations typically 1 to 8 mM (Griffith, Free Radical Biology and Medicine, 1999)

If you dont have enough of this powerful antioxidant in your system, you may be at increased risk for cancer, cardiovascular disease, diabetes, arthritis, digestive issues, and more

1,2 Protein nitration is a post-translational modification that occurs in both prokaryotic and eukaryotic cells primarily on tyrosine residues