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GLP-1 receptor-mediated effects are the most well-characterised and include: Nausea, vomiting, and diarrhoea typically dose-dependent and most prominent during dose escalation Reduced appetite and early satiety Pancreatitis has been reported with GLP-1 receptor agonist class medicines

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So it scares the insurance companies for now

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EMA Decision P/0336/2024: Paediatric investigation plan for retatrutide

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