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At 24 weeks (the last point before people taking a placebo were eligible to switch to orforglipron), people taking a placebo had roughly gained 20 pounds back on average, no matter which drug they were taking originally

Now, new evidence points to the mitochondrial metabolite glutathione, highlighting its central role in helping breast cancer cells break away from the primary tumor, travel through the body, and take root in other tissues

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Strategic Outlook: Preparing for the Next Phase of Product Liability Lawsuits As each of these product liability cases advances through discovery and bellwether preparation, the second half of 2025 will demand even greater precision from legal teams

Timeline: What to Expect The framing below reflects what was observed in controlled trials and the label , not a promise