1 Some common GLP-1 drugs approved by the FDA to help treat weight loss include: Semaglutide injection (Wegovy) 1 Liraglutide (Saxenda) 1 Tirezepatide (Zepbound) 1 Common Digestive Side Effects of GLP-1 Medications Gastrointestinal side effects of GLP-1 medications are not uncommon and can include: Gas (flatulence) and gas pains 1,2 Bloating 1,2 Constipation 1,2 Diarrhea 1,2 How to Manage GLP-1 Gas and Bloating Caused by Weight Loss Drugs Gas and bloating due to constipation caused by weight loss medications can be annoying (and smelly) in your daily life, but they can be easily remedied on your own
Abbreviations DTT: dithiotreitol GSH: glutathione GSSG: oxidized glutathione GST: glutathione transferase e-CAT: erythrocyte catalase e-GST: erythrocyte glutathione transferase
Whats novel about current medications is that they address more than one target or pathway in both these systems, working well to reduce hunger, enhance satiety, and facilitate lower intake leading to weight reduction
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Since none of the GLP-1RA are approved in pregnancy, a cohort study approved the potency of liraglutide, in early pregnancy, despite its adverse outcomes such as preterm birth, preeclampsia and gestational diabetes mellitus (GDM) (90)
doi: 10.1016/j.redox.2023.102917