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Bruising severity and frequency vary considerably among individuals
GLP-1 receptor agonists should only be continued if there is a beneficial metabolic response, defined as a reduction of at least 11 mmol/mol (1.0%) in HbA1c and a weight loss of at least 3% of initial body weight at six months
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The delivery methods also differ considerably - while injections provide controlled, consistent release of medication through subcutaneous administration, patches rely on unproven transdermal delivery that cannot effectively transport the hormone through the skin barrier
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