Zinc Deficiency: Prolonged use of glutathione supplements may lead to low zinc levels in the body
A review on the role of glutathione in cellular function emphasizes that glutathione control the oxidative-reductive state within cells through modifying protein S-glutathionylation, influencing multiple cellular signaling pathways and responding to environmental variations inside and outside cells ( Generally, glutathiones role in cellular function positions it as a possible therapeutic agent for protecting periodontal health by its antioxidant properties and its capacity to maintain oxidative-reductive balance
This in turn requires the availability of reliable tools for confirming the diagnosis of OS and evaluation its severity
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The -SH groups on these residues act as strong nucleophiles, which can conjugate with a variety of molecules, including other glutathione molecules
In rare cases, mild gastrointestinal symptoms such as nausea, bloating, or abdominal discomfort may occur