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They are used to: Improve glycemic management in people with diabetes Support weight loss in individuals with overweight or obesity Reduce cardiovascular risk in certain patient populations Most recently, to treat moderate to severe obstructive sleep apnea These medications are typically prescribed at FDA-approved doses and titrated gradually to manage gastrointestinal side effects like nausea, diarrhea, and upset stomach

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One possibility is that actin patches buffer the forces exerted on the nuclei by chromatin bridges thus preventing breakage

This is fundamentally different from how minoxidil works, which primarily dilates blood vessels, or how finasteride works, which blocks DHT production

doi: 10.1016/j.obpill.2025.100209.eCollection 2025 Dec