At the same time, it reduces appetite by acting on areas of the brain that control hunger, making it a dual-action drug for managing both diabetes and weight
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Helps with tight muscles and sore bodies
Treatment with active comparators semaglutide 1 mg, insulin degludec and insulin glargine resulted in mean heart rate increases of 4, 1 and 1 bpm, respectively
The pivotal Phase 2 trial (Jastreboff et al., 2023) did not stratify results by time of injection, and no head-to-head timing studies have been conducted to date
[16] [17] Whether these risks apply to retatrutide specifically is not yet established, as the full long-term safety profile remains unknown pending Phase 3 data