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The DRI modification makes the peptide backbone unrecognizable to endogenous aminopeptidases, carboxypeptidases, and endopeptidases, extending functional persistence from minutes to an estimated hours-to-days range
Whilst no patient exhibited an objective response, eight had stable disease, with one patient having stable disease for 18 weeks
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Genes with altered gene regulatory sequences include LINC00339, VEZT CDC42, and CDKN2A-AS1
G protein-coupled receptors targeting insulin resistance, obesity, and type 2 diabetes mellitus
[Abstract]2023 Jan-Dec:42:9603271231178015
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