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Tirzepatide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN2)
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Wegovy is a glucagon-like peptide-1 (GLP-1) receptor agonist licensed by the MHRA for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity
Semaglutide itself is generally well-tolerated with GI side effects (nausea, constipation) as the most common concerns
Naturally occurring GLP-1 is an incretin hormone that is secreted within the gastrointestinal tract upon food ingestion
Because glutathione works by inhibiting melanin production at the source, it's considered one of the more effective non-invasive options for gradually improving melasma and hyperpigmentation over time
