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In the landmark STEP clinical trial program, semaglutide produced an average weight loss of 14.9% of body weight over 68 weeks a level of efficacy that had previously only been achievable through bariatric surgery

Biochem Biophys Res Commun 1998;246:589-595

Intervenes in the process of energy metabolization

Who benefits most B12 shots make the biggest difference for people who are genuinely low, including vegans and vegetarians, older adults, and people with conditions like Crohn's disease that limit absorption

While semaglutide (which is in Ozempic) is currently an off-label treatment for weight management, NICE (National Institute for Health and Care Excellence) in the United Kingdom recommended it for obesity treatment in February 2022

PlexusDx Precision Peptide Genetic Test examines key variants (GIPR rs1800437, FTO rs9939609, MC4R rs17782313) that may help provide context for your provider's medication selection