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Mitochondrial dysfunction as a mechanism of drug-induced hepatotoxicity: Current understanding and future perspectives

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Conversely, smaller studies exploring acute, peri-procedural administration, such as intravenous Vitamin C combined with E pre-PCI [PREVEC trial (Rodrigo et al., 2014)] or intracoronary Vitamin E during surgery (Section 2.2

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Potential advantages Generally simpler anatomy than gastric bypass No intestinal rerouting Strong option for many first-time bariatric surgery patients Can be a good fit for patients who want a restrictive/metabolic procedure Usually avoids the malabsorption component of bypass Important considerations May worsen or trigger acid reflux in some patients May not be the best option for severe GERD or Barretts esophagus Requires lifelong attention to portion size, protein, vitamins, and habits Some patients may need revision later if reflux or weight regain occurs Gastric Bypass Also called Roux-en-Y gastric bypass Gastric bypass creates a small stomach pouch and reroutes part of the small intestine