When GLP-1 is released, it does four main things in the body: Signals the pancreas to release insulin when blood sugar is elevated Suppresses the release of glucagon (a hormone that raises blood sugar) Slows the rate at which food leaves the stomach Acts on appetite centres in the brain to promote feelings of fullness The GLP-1 your body produces gets broken down within a couple of minutes of being released
the other physiological changes are probably explained by weight loss
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It is postulated that glucagon, GLP-1, and GIP elicit different effects in a variety of tissues, with most actions being complementary and potentially synergistic, and as such targeting them simultaneously can convey certain advantages compared to targeting one peptide alone (Figure 3)
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David Hunter, MD, an associate professor of neurology at UTHealth Houston, not involved in this review, spoke with Medical News Today about its findings