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N Engl J Med 371(26):24772487 Gerber PA, Rutter GA (2017) The role of oxidative stress and hypoxia in pancreatic beta-cell dysfunction in diabetes mellitus

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In both animal models and controlled human studies, DSIP has been associated with modulation of endogenous sleep-regulating systems rather than direct sedative activity, supporting its classification as a neuromodulator rather than a pharmacological hypnotic agent [2]

Witko-SarsatVFriedlanderMNguyen KhoaTCapeillre-BlandinCNguyenACanteloupSet alAdvanced oxidation protein products as novel mediators of inflammation and monocyte activation in chronic renal failure