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Jakate S, Demeo M, John R, Tobin M, Keshavarzian A

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Attempts at generating BODIPY-conjugated C1-27 were unsuccessful as it proved to be unstable

For targets with no existing fluorophore conjugated antibody the following primary antibodies were used: anti NRF2 polyclonal (1:200, Thermofisher, PA5-27882)

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Examples of drugs that are in the latter class include the anti-malarial drugs dapsone and primaquine, as well as rasburicase which is normally used in the treatment tumor lysis syndrome in patients undergoing chemotherapy for hematologic cancers, but has also been used to reduce the hyperuricemia associated with gout