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PMCID: PMC8114704

Rather than activating the growth hormone receptor, AOD 9604 functions as a pathway-specific modulator of lipid metabolism, enabling investigation of lipolysis and energy regulation in experimental systems without engagement of IGF-1mediated endocrine signaling

There is no digestive step and no intrinsic factor requirement, which is the entire point for anyone whose absorption is compromised

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That link is part of why gut flares may come with joint aches, skin issues, or tiredness