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Excessive hepcidin causes increased binding to FPN, the only identified mammalian intracellular iron exporter, leading to increased internalization and degradation of hepcidin-FPN that aggravates iron deposition in cells (26)

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Breitkreutz Published in Proceedings of the Nutrition 1 November 2000 Medicine, Biology Application of Glutathione as Anti-Oxidative and Anti-Aging Drugs Takujiro Homma 1, Junichi Fujii Wataru Aoi,Yumi Ogaya,Maki Takami,Toru Konishi,Yusuke Sauchi,Eun Young Park,Sayori Wada,Kenji Sato4 Division of Applied Biosciences, Graduate School of AgricultureKyoto UniversityKyotoJapan Glutathione in Brain Disorders and Aging Y