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By extending the feeling of satiety, it becomes much easier to maintain the caloric deficit required for weight loss without feeling deprived

These results come from Phase 2 clinical trials published in NEJM (2023) and ongoing Phase 3 trials

Nearly one-third report neutral feelings and another third report dissatisfaction

[194] Niacin is not being studied as a neuroprotective agent in glaucoma, and patients should not substitute niacin for nicotinamide, as doing so may increase the risk of adverse effects

cholesterol level or BMI

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