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A propensity score matching method was used to balance covariates between the two groups
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Skin lightening was noticed in a patient as a side effect of large doses of glutathione, which was given for some other disease, and then onwards, it became more popular as a skin lightening agent
Potential side effects of berberine may include headaches, digestive upset (such as nausea or diarrhea), abdominal discomfort, and, in rare cases, skin irritation
169 Ni, Y
Sheard 2004
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