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The variable R group gives rise to the four most commonly known cobalamins: cyanocobalamin (CNCbl), methylcobalamin (MeCbl), adenosylcobalamin (AdCbl, also known as cobamamide or 5-deoxyadenosylcobalamin), and hydroxocobalamin (OHCbl)

Pyroglutamate, a glutamate analogue and precursor, helps maintain intracellular glutamate concentrations and has also been linked to various osmoprotective roles 76

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GHRP-6 may cause weight and adipose tissue gain if insulin is present

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