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However, we would suggest that future clinical trials should aim to assess the cost-effectiveness of screening older people with obesity who are undergoing weight management interventions for evidence of sarcopenia, through clinical evaluation including hand grip tests, which are accurate biomarkers for overall strength and function, bone mineral density and consequent fracture risk, and cardiometabolic disease [123]

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Progressive resistance training, minimum 3 sessions per week

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April 29, 2026 Tesamorelin metabolic syndrome research integrating visceral fat, glucose regulation, lipid profile, inflammatory markers, and hepatic steatosis endpoints