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acknowledges support from the NIH (R35GM156596, R01CA259111 and R01CA298386)
These findings align with evidence that GLP-1 is widely expressed and secreted within the nervous system, supporting potential effects in either the central or peripheral nervous system, the researchers wrote
In ATTAIN-MAINTAIN, patients who switched from semaglutide or tirzepatide to orforglipron broadly maintained their losses, which is a sensible secondary commercial position
Lind M, Garcia-Rodriguez LA, Booth GL, Cea-Soriano L, Shah BR, Ekeroth G, Lipscombe LL: Mortality trends in patients with and without diabetes in Ontario, Canada and the UK from 1996 to 2009: a population-based study
11-13 Although the primary mechanisms through which GLP-1 regulates alcohol-related behaviors are not fully elucidated, genetic variations in genes encoding for the GLP-1 receptor have been identified as being associated with both AUD and at-risk drinking
