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(J Orthop Res 2008): reparacin de msculo cudriceps tras transeccin

A primary concern in the initial evaluation is the identification or exclusion of adrenal insufficiency, as it represents the only clinical scenario necessitating immediate, life-saving hormone replacement therapy [147]

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However, several theoretical indirect mechanisms warrant clinical consideration

Defects in SDH subunits lead to succinate accumulation and oncometabolite-driven pseudohypoxia and are strongly linked to hereditary paragangliomas, pheochromocytomas and certain renal cell carcinomas, underscoring the essential role of complex II in metabolic and redox homeostasis 78,79