Surgery, Recovery, And Scars If you choose surgery, it will be performed in an accredited hospital with full anaesthetic and nursing support
Since arcuate POMC neurons have been shown to be activated by GLP-1R agonists [6,7,14], we used the iDTR mouse model to selectively ablate POMC neurons [11-13]
Pregnant or nursing a baby, or if you have any known or suspected medical condition(s) and/or are taking any prescription or OTC medication(s)
Even though lower doses are presumably safer, using them would still require a new pre-IND safety justification, dose-range toxicology studies, and possibly a new manufacturing lot release. That would add ~12 years of delay
While research suggests having a higher weight may increase your risk for certain conditions, people can be healthy at every size
And the GLP-1 conversation, as it is currently happening, is leaving them almost entirely out