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In one of the AWARD studies Efficacy and Safety of Dulaglutide Versus Sitagliptin After 52 Weeks in Type 2 Diabetes in a Randomized Controlled Trial (AWARD-5), it showed that Trulicity was more effective in causing weight loss compared to another type 2 diabetes medication, called sitagliptin (a DPP-4 inhibitor)

GLP-1 also acts in the hindbrain, particularly in the caudal nucleus of the solitary tract, which integrates visceral sensory information and stress signals

Unlike tirzepatide, which activates both GLP-1 and GIP receptors, MariTide is a GIPR antagonist antibody/GLP-1R peptide agonist conjugate which means that it activates GLP-1 receptors while blocking GIP responses

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Obecnie zwizek funkcjonuje jako lek na recept zarejestrowany w Polsce pod nazw Scenesse

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