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This dual mechanism enhances glucosedependent insulin secretion while suppressing glucagon release, slowing gastric emptying, and promoting satiety through central appetite regulation [2]
Ruof leads the Refine Her longevity and hormone optimization programs, focusing on perimenopause, menopause, metabolic health, and whole-body vitality
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Early studies suggest retatrutide may lead to more weight loss than current options, with people losing around 24% of their body weight compared to about 21% with Zepbound and 15% with Wegovy
However, because semaglutide works so well to control blood sugar, patients with diabetes may experience spikes in blood sugar