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The PPP in erythrocytes is the only pathway for these cells to produce NADPH, therefore, any defect in the production of NADPH, such as due to deficiencies in glucose-6-phosphate dehydrogenase, will have profound effects on erythrocyte survival

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This helps the liver to perform its normal functions

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10.1021/acsnano.9b00892 ACS Nano 170 ZhangH.DengT.LiuR.NingT.YangH.LiuD.et al (2020a)

Additionally, diets high in fluoride have similarly been observed to decrease E-C3bRR and increase E-ICRR in broiler erythrocytes (70)