Thats because the mechanism is indirect
Gallbladder problems are another concern
First-line serplulimab or placebo plus chemotherapy in PD-L1-positive esophageal squamous cell carcinoma: a randomized, double-blind phase 3 trial
Cellular metabolism involves the chemical breakdown of oxygen molecules
Seek immediate medical attention (call 911 for severe symptoms) if you experience: Chest pain, pressure, or discomfort, particularly if new or worsening Severe shortness of breath or difficulty breathing at rest Rapid or irregular heartbeat accompanied by dizziness or lightheadedness Swelling in the legs, ankles, or abdomen that develops suddenly or worsens Unexplained fatigue or exercise intolerance that significantly limits daily activities These symptoms may indicate cardiovascular complications unrelated to tirzepatide itself but requiring urgent evaluation, especially in patients with diabetes and obesity who have elevated baseline cardiovascular risk
The lab work is thorough, checking for contraindications that other providers might miss