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Singly-housed rodents may have increased adiposity 101 and, moreover, singly-housed mice in standard caging can engage in coprophagy of their own feces that may impact their cecal microbiome 102

Glutathione deficiency correlates with chronic disease and can be replenished from exogenous sources, such as natural glutathione in food and glutathione supplements

10.1016/j.fct.2008.11.013 48 EllulP.RosenzwajgM.PeyreH.FourcadeG.Mariotti-FerrandizE.TrebossenV.et al (2021)

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Such diseases often arise from impaired vascular function, leading to severe complications such as myocardial infarction and cerebrovascular accidents (Prakash Babu et al., 2019

For people with type 2 diabetes, microdosing requires additional monitoring because even low doses can affect blood glucose levels