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The cost of manufacturing GLP-1 anti-obesity drugs is low April 10, 2024 Source: Barber, MJ et al JAMA Network Open March 27, 2024 LINK (Calculated from the Appendix eTable 1 and eFigure 1, assuming the highest cost pens ($2.50 each) and doubling cost of API to account for wastage) New information about the potential medical benefits of GLP-1 medications tantalizes us
Keep medication in its original carton to protect from light
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The pre-proglucagon system constitutes interesting candidates as potential targets for new anti-obesity drugs
The AACE/ACE obesity clinical practice guidelines recommend treating obesity as a chronic disease requiring long-term pharmacological management when lifestyle intervention alone is insufficient, and explicitly note that comorbidity burden should guide medication selection throughout the treatment course
The downside is larger injection volumes and faster depletion of vial contents (since you are pulling more liquid per dose)
