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Cancer Cell 40 , 624638.e9 (2022)

Synthetic medicines Synthetic drugs have been researched and developed in recent modern times, a proportion of which have already been in clinical use for the treatment of various diseases, such as myocardial infarction, heart failure, diabetes, hypertension, oncology, and sepsis

Whether similar trigger-wave dynamics can be sustained in complex three-dimensional tissues, where geometry, extracellular matrix, and heterogeneous antioxidant buffering may substantially alter propagation behavior, remains an important open question and a critical test of the models physiological generalizability

FDX2, an iron-sulfur cluster assembly factor, is essential to prevent cellular senescence, apoptosis or ferroptosis of ovarian cancer cells

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