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What we know about B12 supplementation with semaglutide The combination of B12 and semaglutide is generally considered safe, as no drug reactions have been reported between these medications

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These tend to emerge early in a protocol and resolve as the body adjusts

It is therefore possible to be B12 deficient despite having high B12 blood levels for example, if the vitamin cannot correctly bind to transport molecules (6)

Theoretical and stack-level concerns Both compounds promote angiogenesis, which is the intended mechanism for repair but is also a relevant pathway in tumor growth

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