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Bulletin of Experimental Biology and Medicine, 158 , 726-728
Nature 452 , 896899 (2008)
However, it is due to the fully humanized sequence that the half-life of Beinaglutide in vivo is extremely short and the frequency of 3 injections per day is much criticized by patients
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However, there are also studies showing that the accumulation of zinc in mitochondria can increase mitochondrial ROS (mtROS) levels and subsequently activate the downstream signaling molecule nuclear transcription factor-kappa B (NF-B) [30]
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