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Drugs Today (Barc) (2013) 49(9):53753

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Developmental differences in drug metabolism Hepatic drug metabolism is classically thought to occur via two distinct routes: phase I and phase II metabolism.6 Phase I reactions are frequently mediated by cytochrome P450 enzymes, such as CYP2E1 in the case of acetaminophen

International Immunopharmacology, 75 , Article 105801

Even more striking, among patients who did develop acute pancreatitis, GLP-1 RA users had fewer complications (including reduced rates of sepsis, AKI, shock, mechanical ventilation) and lower all-cause mortality