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Each enzyme that does the converting requires specific nutrients, called cofactors, including glycine, magnesium, and vitamin B6

However, emerging evidence suggests that their benefits extended beyond glycaemic control, with pleiotropic effects on multiple organ systems, including significant anti-fibrotic effects

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That dose - 1.0 mg - is the glycemic-management dose of semaglutide, lower than the 2.4 mg weekly dose used for chronic weight management in the Wegovy formulation