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Studies revealed that in aged rhesus monkeys (20-26 years), Epithalon increased melatonin levels more than 3-fold compared to baseline, restoring circadian patterns characteristic of younger animals

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Naturally occurring amino acids have an L chiral configuration, while the DRI peptides appear to be composed of D chiral amino acids

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This research gap reflects the challenging regulatory landscape for peptides and the lack of pharmaceutical industry interest in compounds that cannot be patented

Cochrane Database of Systematic Reviews (2019) Rejdak K, Sienkiewicz-Jarosz H, Bienkowski P, et al