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How you see the clinical path evolving: will tetra-agonists be positioned primarily for severe obesity first, or could they compete with existing dual/tri agonists in broader metabolic indications?

Lack of quality control: Since compounded drugs are not subject to the same rigorous FDA standards as commercially available drugs, their quality and potency can be inconsistent.Side effects of compounded drugs can include potential contamination due to poor compounding practices, incorrect dosage due to mixing errors, allergic reactions to added ingredients, and severe adverse events like infections, depending on the specific drug and compounding process, as compounded medications are not subject to the same rigorous FDA regulations as commercially available drugs

PMID: 20923958

These findings are mechanistically coherent with GHK-Cus anti-inflammatory NF-kB activity because the secondary injury cascade in SCI involves microglial activation, sustained pro-inflammatory cytokine release, and reactive oxygen species generation

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