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I believe these medications have such broad effects because a lot of health problems begin with disruptions in insulin resistance [abnormalities in how the body handles glucose] and inflammation, says Jamy Ard, MD, a professor of epidemiology and prevention at Wake Forest University School of Medicine in Winston-Salem, North Carolina

Clinical and Translational Medicine, 14 (3), Article e1636

But then as you get into other layers, like exposure to air pollution, microplastics forever chemicals, social isolation, time in nature

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Mittal, M., et al., Reactive oxygen species in inflammation and tissue injury

For patients outside the typical age range for weight loss injections, or those who prefer non-injectable options, several evidence-based alternatives exist