semaglutide come in pill form The Ozempic Has Arrived. Here's Who It's for, Plus How to Get It Oral Semaglutide for Weight Loss:

Reuters, 2023

Across these studies, weight loss was consistently greater with semaglutide than with placebo, and the weight loss was associated with improvements in cardiometabolic risk factors including blood pressure, waist circumference, lipid profiles, and inflammatory markers

In DKD, damaged tubule cells activate macrophages and the NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome, making a lot of ROS(Fang et al., 2025)

However, rapid weight loss risks sodium deficiency

Remission of prurigo pigmentosa after breaking ketogenic diet and resuming regular diet

Another concern with GLP-1 agonists is the loss of body mass, including fat and skeletal muscle, causing some patients to feel a loss of strength