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These symptoms seldom respond well to conventional therapies (Braunwald 2001

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If side effects become problematic, lowering the dose before attempting further increases can help

Transcriptomics and biochemical evidence of trigonelline ameliorating learning and memory decline in the senescence-accelerated mouse prone 8 (SAMP8) model by suppressing proinflammatory cytokines and elevating neurotransmitter release

PMID: 17389505

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