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Weeks two through four

Begin eating smaller, more frequent meals

Many patients do not realize that weight-loss medications require special perioperative consideration, so explicit disclosure is critical even if not directly asked

The consequences of undereating protein in a six-hour window are not immediately obvious

A key controller of this cellular defense mechanism is the Nrf2 (nuclear factor erythroid 2related factor 2)-antioxidant response element (ARE) pathway