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Both medications carry a black-box warning for thyroid C-cell tumors, including medullary thyroid carcinoma, and are contraindicated in patients with personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2

However, the absence of DsbA shifted the periplasmic thiol-redox potential from -228 mV to a more reducing -243 mV and the capacity to re-oxidize periplasmic roGFP2 after a reductive pulse was significantly decreased

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Soon D, Kothare PA, Linnebjerg H, Park S, Yuen E, Mace KF, et al

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