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As a limitation, the series was relatively small and no information on the type of trauma and the involved energy as well as trauma imaging was available
M., Christensen, M
Oral tablets like Rybelsus (the FDA-approved oral semaglutide) use a special compound called SNAC to protect against stomach acid, yet still achieve only 0.4-1% bioavailability
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However, the clinical advancement of oridonin faced limitations [24, 25], stemming not only from its unclear molecular mechanisms but also due to hydrophobicity and deficient targeting capabilities [26,27,28,29]
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