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Inhibition of dipeptidyl peptidase IV with NVP-DPP728 increases plasma GLP-1 (7-36 amide) concentrations and improves oral glucose tolerance in obese Zucker rats
Specifically, reduced GLP-1 was associated with altered expression of the pro-inflammatory macrophage marker CD86
NAD+ (Nicotinamide Adenine Dinucleotide) is a powerful coenzyme that plays a key role in cellular function and energy production
Impact of obesity and the obesity paradox on prevalence and prognosis in heart failure
26,27 The rate of gastric emptying is particularly relevant as it is a major determinant of post-meal glucose levels in people with and without diabetes and may, hence, influence treatment regimens
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