While semaglutide is generally well tolerated, some people experience mild to moderate side effects such as nausea, vomiting, diarrhea, constipation, or abdominal discomfortsymptoms that often improve as your body adjusts to the medication
To get closer to cause-and-effect answers, researchers conducted a target-trial emulation in 2025
If you miss a scheduled dose, it is important to take your missed dose as soon as possible
doi: 10.1111/febs.13827 101 WuJRenBWangDLinH
Others provide vials with no bacteriostatic water and expect you to source your own, giving you complete control over concentration but requiring more knowledge and preparation
Among those who stayed on treatment for the full 68 weeks, cagrilintide 2.4 mg delivered an average of about 12% body weight reduction , compared to 2.3% for placebo