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Interestingly, the first 22 amino acids of the N-terminus are essential for protein kinase C-mediated phosphorylation of DAT [44]
Sehgal, Jena Shaw Tronieri, Lyle Ungar, Sharath Chandra Guntuku
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Unlike current injectable GLP-1 therapies, Orforglipron is taken orally, opening new opportunities for patient compliance and accessibility
Weight gain during menopause is often hormonally driven
If GI side effects are severe at any step, hold the current dose for an extra 4 weeks before escalating
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